Introducing the Microsoft Climate Research Initiative

Addressing and mitigating the effects of climate change requires a collective effort, bringing our strengths to bear across industry, government, academia, and civil society. As we continue to explore the role of technology to advance the art of the possible, we are launching the Microsoft Climate Research Initiative (MCRI). This community of multi-disciplinary researchers is working together to accelerate cutting-edge research and transformative innovation in climate science and technology. MCRI enables us to bring  

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(De)ToxiGen: Leveraging large language models to build more robust hate speech detection tools

It’s a well-known challenge that large language models (LLMs)—growing in popularity thanks to their adaptability across a variety of applications—carry risks. Because they’re trained on large amounts of data from across the internet, they’re capable of generating inappropriate and harmful language based on similar language encountered during training.   Content moderation tools can be deployed to flag or filter such language in some contexts, but unfortunately, datasets available to train these tools often fail to capture the  

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Partnering people with large language models to find and fix bugs in NLP systems

Advances in platform models—large-scale models that can serve as foundations across applications—have significantly improved the ability of computers to process natural language. But natural language processing (NLP) models are still far from perfect, sometimes failing in embarrassing ways, like translating “Eu não recomendo este prato” (I don’t recommend this dish) in Portuguese to “I highly recommend this dish” in English (a real example from a top commercial model). These failures continue to exist in part because finding and fixing bugs […]

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MoLeR: Creating a path to more efficient drug design

Drug discovery has come a long way from its roots in serendipity. It is now an increasingly rational process, in which one important phase, called lead optimization, is the stepwise search for promising drug candidate compounds in the lab. In this phase, expert medicinal chemists work to improve “hit” molecules—compounds that demonstrate some promising properties, as well as some undesirable ones, in early screening. In subsequent testing, chemists try to adapt the structure of hit molecules to improve their biological […]

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