GPT-4 Empowered Coscientist Revolutionizes AI-Driven Chemical Synthesis
In a groundbreaking development, chemists have harnessed the power of artificial intelligence to design and execute intricate chemical reactions using a robotic laboratory set-up. Named Coscientist, this system utilizes the latest large language models (LLMs), including GPT-4, to autonomously plan, code, and conduct reactions, producing compounds such as paracetamol and aspirin in real-life laboratory settings.
Led by chemist Gabe Gomes from Carnegie Mellon University, the research team detailed their innovative approach in a report published in Nature on December 20. Gomes expressed his awe at witnessing a non-organic intelligence autonomously execute a human-invented chemical reaction, describing it as a “holy crap” moment.
The system leverages the capabilities of GPT-4 and other advanced LLMs to analyze chemical literature, design reaction pathways prompted by human input, and